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Targeting ubiquitin-specific protease 8 sensitizes anti-programmed death-ligand 1 immunotherapy of pancreatic cancer
Programmed death-1 (PD-1) and its ligand programmed death-ligand 1 (PD-L1) help tumor cells evade immune surveillance, and are regarded as important targets of anti-tumor immunotherapy. Post-translational modification of PD-L1 has potential value in immunosuppression. Here, we identified that ubiqui...
Autores principales: | Yang, Hanshen, Zhang, Xiaozhen, Lao, Mengyi, Sun, Kang, He, Lihong, Xu, Jian, Duan, Yi, Chen, Yan, Ying, Honggang, Li, Muchun, Guo, Chengxiang, Lu, Qingsong, Wang, Sicheng, Su, Wei, Liang, Tingbo, Bai, Xueli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950432/ https://www.ncbi.nlm.nih.gov/pubmed/36539510 http://dx.doi.org/10.1038/s41418-022-01102-z |
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