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Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Anillin (ANLN) is a mitosis-related protein that promotes contractile ring formation and cytokinesis, but its cell cycle-dependent degradation mechanisms in cancer cells remain unclear. Here, we show that high expression of ANLN promotes cytokinesis and proliferation in esophageal squamous cell carc...

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Detalles Bibliográficos
Autores principales: Cao, Yu-Fei, Xie, Lei, Tong, Bei-Bei, Chu, Man-Yu, Shi, Wen-Qi, Li, Xiang, He, Jian-Zhong, Wang, Shao-Hong, Wu, Zhi-Yong, Deng, Dan-Xia, Zheng, Ya-Qi, Li, Zhi-Mao, Xu, Xiu-E, Liao, Lian-Di, Cheng, Yin-Wei, Li, Li-Yan, Xu, Li-Yan, Li, En-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950447/
https://www.ncbi.nlm.nih.gov/pubmed/36526897
http://dx.doi.org/10.1038/s41418-022-01104-x