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GRHL2 and AP2a coordinate early surface ectoderm lineage commitment during development
Ectodermal dysplasias including skin abnormalities and cleft lip/palate result from improper surface ectoderm (SE) patterning. However, the connection between SE gene regulatory networks and disease remains poorly understood. Here, we dissect human SE differentiation with multiomics and establish GR...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950457/ https://www.ncbi.nlm.nih.gov/pubmed/36843855 http://dx.doi.org/10.1016/j.isci.2023.106125 |