GRHL2 and AP2a coordinate early surface ectoderm lineage commitment during development

Ectodermal dysplasias including skin abnormalities and cleft lip/palate result from improper surface ectoderm (SE) patterning. However, the connection between SE gene regulatory networks and disease remains poorly understood. Here, we dissect human SE differentiation with multiomics and establish GR...

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Detalles Bibliográficos
Autores principales: Collier, Ann E., Piekos, Samantha N., Liu, Angela, Pattison, Jillian M., Felix, Franco, Bailetti, Alessandro A., Sedov, Egor, Gaddam, Sadhana, Zhen, Hanson, Oro, Anthony E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950457/
https://www.ncbi.nlm.nih.gov/pubmed/36843855
http://dx.doi.org/10.1016/j.isci.2023.106125

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