Cargando…

The tumor biological significance of RNF43 and LRP1B in gastric cancer is complex and context-dependent

Gastric cancer (GC) is the fifth most common cancer in the world with a poor prognosis. Both RNF43 and LRP1B function as tumor suppressors in the Wnt signaling pathway and have been described to be frequently mutated in GC. In this study of a large and well characterized cohort of 446 GCs we explore...

Descripción completa

Detalles Bibliográficos
Autores principales: Holm, Bente, Barsuhn, Stephan, Behrens, Hans-Michael, Krüger, Sandra, Röcken, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950470/
https://www.ncbi.nlm.nih.gov/pubmed/36823311
http://dx.doi.org/10.1038/s41598-023-30294-8