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The tumor biological significance of RNF43 and LRP1B in gastric cancer is complex and context-dependent
Gastric cancer (GC) is the fifth most common cancer in the world with a poor prognosis. Both RNF43 and LRP1B function as tumor suppressors in the Wnt signaling pathway and have been described to be frequently mutated in GC. In this study of a large and well characterized cohort of 446 GCs we explore...
Autores principales: | Holm, Bente, Barsuhn, Stephan, Behrens, Hans-Michael, Krüger, Sandra, Röcken, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950470/ https://www.ncbi.nlm.nih.gov/pubmed/36823311 http://dx.doi.org/10.1038/s41598-023-30294-8 |
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