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Harnessing TRAIL-induced cell death for cancer therapy: a long walk with thrilling discoveries
Tumor necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL) can induce apoptosis in a wide variety of cancer cells, both in vitro and in vivo, importantly without killing any essential normal cells. These findings formed the basis for the development of TRAIL-receptor agonists (TRAs) for c...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950482/ https://www.ncbi.nlm.nih.gov/pubmed/36195672 http://dx.doi.org/10.1038/s41418-022-01059-z |