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Osteoprotegerin deficiency aggravates methionine–choline-deficient diet-induced nonalcoholic steatohepatitis in mice

Clinical studies have shown that osteoprotegerin (OPG) is reduced in patients with nonalcoholic steatohepatitis (NASH), but the underlying mechanisms are unclear. The current study focuses on the role of OPG in the NASH pathogenesis. OPG knockout mice and wild-type control mice fed a methionine chol...

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Detalles Bibliográficos
Autores principales: Wu, Shaobo, Wu, Yao, Lin, Lan, Ruan, Changshun, Li, Fang, Chen, Rong, Du, Hongxin, Zhang, Xianxiang, Luo, Xiaohe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950492/
https://www.ncbi.nlm.nih.gov/pubmed/36823220
http://dx.doi.org/10.1038/s41598-023-30001-7