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Osteoprotegerin deficiency aggravates methionine–choline-deficient diet-induced nonalcoholic steatohepatitis in mice
Clinical studies have shown that osteoprotegerin (OPG) is reduced in patients with nonalcoholic steatohepatitis (NASH), but the underlying mechanisms are unclear. The current study focuses on the role of OPG in the NASH pathogenesis. OPG knockout mice and wild-type control mice fed a methionine chol...
Autores principales: | Wu, Shaobo, Wu, Yao, Lin, Lan, Ruan, Changshun, Li, Fang, Chen, Rong, Du, Hongxin, Zhang, Xianxiang, Luo, Xiaohe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950492/ https://www.ncbi.nlm.nih.gov/pubmed/36823220 http://dx.doi.org/10.1038/s41598-023-30001-7 |
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