Dysfunction of the noradrenergic system drives inflammation, α-synucleinopathy, and neuronal loss in mouse colon

Clinical and pathological evidence revealed that α-synuclein (α-syn) pathology seen in PD patients starts in the gut and spreads via anatomically connected structures from the gut to the brain. Our previous study demonstrated that depletion of central norepinephrine (NE) disrupted brain immune homeo...

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Detalles Bibliográficos
Autores principales: Song, Sheng, Tu, Dezhen, Meng, Chengbo, Liu, Jie, Wilson, Belinda, Wang, Qingshan, Shih, Yen-Yu Ian, Gao, Hui-Ming, Hong, Jau-Shyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950510/
https://www.ncbi.nlm.nih.gov/pubmed/36845109
http://dx.doi.org/10.3389/fimmu.2023.1083513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950510/
https://www.ncbi.nlm.nih.gov/pubmed/36845109
http://dx.doi.org/10.3389/fimmu.2023.1083513

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