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A photodynamic-mediated glutamine metabolic intervention nanodrug for triple negative breast cancer therapy

“Glutamine addiction” is a unique feature of triple negative breast cancer (TNBC), which has a higher demand for glutamine and is more susceptible to glutamine depletion. Glutamine can be hydrolyzed to glutamate by glutaminase (GLS) for synthesis of glutathione (GSH), which is an important downstrea...

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Detalles Bibliográficos
Autores principales: Yu, Cancan, Wang, Ningning, Chen, Xiangwu, Jiang, Yue, Luan, Yuxia, Qin, Wen, He, Wenxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950525/
https://www.ncbi.nlm.nih.gov/pubmed/36846308
http://dx.doi.org/10.1016/j.mtbio.2023.100577