Ectopic RING activity at the ER membrane differentially impacts ERAD protein quality control pathways

Endoplasmic reticulum-associated degradation (ERAD) is a protein quality control pathway that ensures misfolded proteins are removed from the ER and destroyed. In ERAD, membrane and luminal substrates are ubiquitylated by ER-resident RING-type E3 ubiquitin ligases, retrotranslocated into the cytosol...

Descripción completa

Detalles Bibliográficos
Autores principales: Mehrtash, Adrian B., Hochstrasser, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article Collection: Protein Synthesis and Degradation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950527/
https://www.ncbi.nlm.nih.gov/pubmed/36682496
http://dx.doi.org/10.1016/j.jbc.2023.102927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950527/
https://www.ncbi.nlm.nih.gov/pubmed/36682496
http://dx.doi.org/10.1016/j.jbc.2023.102927

Ejemplares similares