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Analysis of mammalian circadian clock protein complexes over a circadian cycle

Circadian rhythmicity is maintained by a set of core clock proteins including the transcriptional activators CLOCK and BMAL1, and the repressors PER (PER1, PER2, and PER3), CRY (CRY1 and CRY2), and CK1δ. In mice, peak expression of the repressors in the early morning reduces CLOCK- and BMAL1-mediate...

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Detalles Bibliográficos
Autores principales: Cao, Xuemei, Wang, Li, Selby, Christopher P., Lindsey-Boltz, Laura A., Sancar, Aziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950529/
https://www.ncbi.nlm.nih.gov/pubmed/36682495
http://dx.doi.org/10.1016/j.jbc.2023.102929