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Protein tyrosine phosphatase 69D is a substrate of protein O-mannosyltransferases 1-2 that is required for the wiring of sensory axons in Drosophila

Mutations in protein O-mannosyltransferases (POMTs) result in severe brain defects and congenital muscular dystrophies characterized by abnormal glycosylation of α-dystroglycan (α-Dg). However, neurological phenotypes of POMT mutants are not well understood, and the functional substrates of POMTs ot...

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Detalles Bibliográficos
Autores principales: Monagas-Valentin, Pedro, Bridger, Robert, Chandel, Ishita, Koff, Melissa, Novikov, Boris, Schroeder, Patrick, Wells, Lance, Panin, Vladislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950532/
https://www.ncbi.nlm.nih.gov/pubmed/36634851
http://dx.doi.org/10.1016/j.jbc.2023.102890