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Decreased Peli1 expression attenuates osteoarthritis by protecting chondrocytes and inhibiting M1-polarization of macrophages

AIMS: Pellino1 (Peli1) has been reported to regulate various inflammatory diseases. This study aims to explore the role of Peli1 in the occurrence and development of osteoarthritis (OA), so as to find new targets for the treatment of OA. METHODS: After inhibiting Peli1 expression in chondrocytes wit...

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Detalles Bibliográficos
Autores principales: Mo, Haokun, Wang, Zhenggang, He, Zhiyi, Wan, Junlai, Lu, Rui, Wang, Chenwen, Chen, Anmin, Cheng, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950670/
https://www.ncbi.nlm.nih.gov/pubmed/36718653
http://dx.doi.org/10.1302/2046-3758.122.BJR-2022-0214.R1