Cargando…

Decreased Peli1 expression attenuates osteoarthritis by protecting chondrocytes and inhibiting M1-polarization of macrophages

AIMS: Pellino1 (Peli1) has been reported to regulate various inflammatory diseases. This study aims to explore the role of Peli1 in the occurrence and development of osteoarthritis (OA), so as to find new targets for the treatment of OA. METHODS: After inhibiting Peli1 expression in chondrocytes wit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mo, Haokun, Wang, Zhenggang, He, Zhiyi, Wan, Junlai, Lu, Rui, Wang, Chenwen, Chen, Anmin, Cheng, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The British Editorial Society of Bone & Joint Surgery 2023
Materias:	Cartilage
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950670/ https://www.ncbi.nlm.nih.gov/pubmed/36718653 http://dx.doi.org/10.1302/2046-3758.122.BJR-2022-0214.R1

Ejemplares similares

GDF11 inhibits abnormal adipogenesis of condylar chondrocytes in temporomandibular joint osteoarthritis
por: Wang, Helin, et al.
Publicado: (2022)

Dihydrocaffeic acid improves IL-1β-induced inflammation and cartilage degradation via inhibiting NF-κB and MAPK signalling pathways
por: Lu, Rui, et al.
Publicado: (2023)

Upregulated ribosome pathway plays a key role in HDAC4, improving the survival rate and biofunction of chondrocytes
por: Guo, Li, et al.
Publicado: (2023)

The role of AGEs in pathogenesis of cartilage destruction in osteoarthritis
por: He, Chao-Peng, et al.
Publicado: (2022)

Clinical evaluation after matrix-associated autologous chondrocyte transplantation: a comparison of four different graft types
por: Binder, Harald, et al.
Publicado: (2021)

Generation of human immortalized chondrocytes from osteoarthritic and healthy cartilage: a new tool for cartilage pathophysiology studies
por: Piñeiro-Ramil, María, et al.
Publicado: (2023)

Histone deacetylase inhibitors attenuated interleukin-1β-induced chondrogenesis inhibition in synovium-derived mesenchymal stem cells of the temporomandibular joint
por: Liao, Wen-ting, et al.
Publicado: (2022)

Molecular crosstalk between articular cartilage, meniscus, synovium, and subchondral bone in osteoarthritis
por: Wang, Maochun, et al.
Publicado: (2022)

A mutation in SLC20A2 (c.C1849T) promotes proliferation while inhibiting hypertrophic differentiation in ATDC5 chondrocytes
por: Li, YiQiang, et al.
Publicado: (2020)

Intra-articular low-dose parathyroid hormone (1-34) improves mobility and articular cartilage quality in a preclinical age-related knee osteoarthritis model
por: Chen, Chung-Hwan, et al.
Publicado: (2021)

Global transcriptome analysis to identify critical genes involved in the pathology of osteoarthritis
por: Zhang, X., et al.
Publicado: (2018)

Whole-transcriptome sequencing of knee joint cartilage from osteoarthritis patients
por: Li, H., et al.
Publicado: (2019)

Modelling osteoarthritis in mice via surgical destabilization of the medial meniscus with or without a stereomicroscope
por: Hu, Wencheng, et al.
Publicado: (2022)

Rejuvenated ageing mesenchymal stem cells by stepwise preconditioning ameliorates surgery-induced osteoarthritis in rabbits
por: Zong, Zhixian, et al.
Publicado: (2020)

Bisphosphonate use is associated with a decreased joint narrowing rate in the non-arthritic hip
por: Kawai, Toshiyuki, et al.
Publicado: (2022)

Validation of joint space narrowing on plain radiographs and its relevance to partial knee arthroplasty: radiological and MRI data from the Osteoarthritis Initiative
por: Khury, Farouk, et al.
Publicado: (2021)

CircStrn3 targeting microRNA-9-5p is involved in the regulation of cartilage degeneration and subchondral bone remodelling in osteoarthritis
por: Li, Bin, et al.
Publicado: (2023)

Comparative effect of platelet- and mesenchymal stromal cell-derived extracellular vesicles on human cartilage explants using an ex vivo inflammatory osteoarthritis model
por: Forteza-Genestra, Maria A., et al.
Publicado: (2023)

Interleukin-1 receptor antagonist protein (IL-1Ra) and miR-140 overexpression via pNNS-conjugated chitosan-mediated gene transfer enhances the repair of full-thickness cartilage defects in a rabbit model
por: Zhao, R., et al.
Publicado: (2019)

The effect induced by alternated mechanical loading on Notch-1 in mandibular condylar cartilage of growing rabbits
por: Yan, Fan, et al.
Publicado: (2021)

The role of histone deacetylase 4 during chondrocyte hypertrophy and endochondral bone development
por: Chen, Zhi, et al.
Publicado: (2020)

The molecular mechanism study of COMP involved in the articular cartilage damage of Kashin-Beck disease
por: Ma, Mei, et al.
Publicado: (2020)

Effect of treadmill training on fibrocartilage complex repair in tendon-bone insertion healing in the postinflammatory stage
por: Tan, Jindong, et al.
Publicado: (2023)

Muscular forces affect the glycosaminoglycan content of joint cartilage: Unloading in human volunteers with the HEPHAISTOS lower leg orthosis
por: Ganse, Bergita, et al.
Publicado: (2015)

Dynamic shear analysis: a novel method to determine mechanical integrity of normal and torn human acetabular labra: Implications for prediction of outcome of repair
por: Woods, A. K., et al.
Publicado: (2018)

The effect of anti-inflammatory and antifibrotic agents on fibroblasts obtained from arthrofibrotic tissue: An in vitro and in vivo study
por: Tang, X., et al.
Publicado: (2018)

A novel organ culture model of a joint for the evaluation of static and dynamic load on articular cartilage
por: Lin, Y-C., et al.
Publicado: (2018)

Tranexamic acid toxicity in human periarticular tissues
por: McLean, M., et al.
Publicado: (2019)

The effectiveness of platelet-rich plasma gel on full-thickness cartilage defect repair in a rabbit model
por: Slimi, Fathia, et al.
Publicado: (2021)

Suramin enhances chondrogenic properties by regulating the p67(phox)/PI3K/AKT/SOX9 signalling pathway
por: Liu, Zi-Miao, et al.
Publicado: (2022)

Integrating genome-wide association study with regulatory SNP annotations identified novel candidate genes for osteoporosis
por: Jia, Yumeng, et al.
Publicado: (2023)

Regeneration of injured articular cartilage using the recombinant human amelogenin protein
por: Helwa-Shalom, Omer, et al.
Publicado: (2023)

Cartilage turnover and intra-articular corticosteroid injections in knee osteoarthritis
por: Klocke, Rainer, et al.
Publicado: (2018)

Peli1 signaling blockade attenuates congenital zika syndrome
por: Luo, Huanle, et al.
Publicado: (2020)

Tert-butylhydroquinone attenuates osteoarthritis by protecting chondrocytes and inhibiting macrophage polarization
por: Zhang, Hua, et al.
Publicado: (2021)

Loss of Cartilage Structure, Stiffness, and Frictional Properties in Mice Lacking PRG4
por: Coles, Jeffrey M, et al.
Publicado: (2010)

Sulforaphane Represses Matrix-Degrading Proteases and Protects Cartilage From Destruction In Vitro and In Vivo
por: Davidson, Rose K, et al.
Publicado: (2013)

Contrast-Enhanced Computed Tomography Enables Quantitative Evaluation of Tissue Properties at Intrajoint Regions in Cadaveric Knee Cartilage
por: Stewart, Rachel C., et al.
Publicado: (2016)

Cartilage Quality (dGEMRIC Index) Following Knee Joint Distraction or High Tibial Osteotomy
por: Besselink, Nick J., et al.
Publicado: (2018)

Epidemiological trends of hand osteoarthritis from 1990 to 2019: Estimates from the 2019 Global Burden of Disease study
por: Wan, Junlai, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2et7a8mgm3k95qnig7ev0uh9eg