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Vaccination using mutated receptor binding domains of SARS-CoV-2: Evidence for partial immune escape but not serotype formation

INTRODUCTION: SARS-CoV-2 has developed a number of Variants of Concern (VOC) with increased infectivity and/or reduced recognition by neutralizing antibodies specific for the receptor binding domain (RBD) of the spike protein. Extended studies of other viruses have shown that strong and broad viral...

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Detalles Bibliográficos
Autores principales: Chang, Xinyue, Liu, Xuelan, Martina, Byron, Zeltins, Andris, Augusto, Gilles, Vogel, Monique, Mohsen, Mona O., Speiser, Daniel E., Bachmann, Martin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950740/
https://www.ncbi.nlm.nih.gov/pubmed/36845100
http://dx.doi.org/10.3389/fimmu.2023.1114396