PALM: a powerful and adaptive latent model for prioritizing risk variants with functional annotations

MOTIVATION: The findings from genome-wide association studies (GWASs) have greatly helped us to understand the genetic basis of human complex traits and diseases. Despite the tremendous progress, much effects are still needed to address several major challenges arising in GWAS. First, most GWAS hits...

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Detalles Bibliográficos
Autores principales: Yu, Xinyi, Xiao, Jiashun, Cai, Mingxuan, Jiao, Yuling, Wan, Xiang, Liu, Jin, Yang, Can
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950853/
https://www.ncbi.nlm.nih.gov/pubmed/36744920
http://dx.doi.org/10.1093/bioinformatics/btad068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950853/
https://www.ncbi.nlm.nih.gov/pubmed/36744920
http://dx.doi.org/10.1093/bioinformatics/btad068

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