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Tranexamic acid for gastrointestinal bleeding: can a reduction in the risk of death be discounted? A systematic review and meta-analysis of individual patient data from 64 724 bleeding patients

OBJECTIVES: HALT-IT was an international, randomised trial which assessed the effects of tranexamic acid (TXA) in 12 009 patients with gastrointestinal (GI) bleeding. The results found no evidence that TXA reduces death. It is widely accepted that results of trials should be interpreted in the conte...

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Detalles Bibliográficos
Autores principales: Ker, Katharine, Mansukhani, Raoul, Shakur-Still, Haleema, Arribas, Monica, Beaumont, Danielle, Roberts, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950890/
https://www.ncbi.nlm.nih.gov/pubmed/36813490
http://dx.doi.org/10.1136/bmjopen-2021-059982