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A combination therapy of bortezomib, CXCR4 inhibitor, and checkpoint inhibitor is effective in cholangiocarcinoma in vivo

Cholangiocarcinoma (CCA) is a biliary tree malignancy with a dismal prognosis. Tumor microenvironment (TME), including cancer-associated fibroblasts (CAFs) has been shown to be involved in drug resistance. To model the interactions between cancer cells and the TME, we established CCA complex patient...

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Detalles Bibliográficos
Autores principales: Li, Ling, Zhou, Yang, Zhang, Yicheng, Hu, Haijie, Mao, Hai-Quan, Selaru, Florin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950944/
https://www.ncbi.nlm.nih.gov/pubmed/36843847
http://dx.doi.org/10.1016/j.isci.2023.106095