Standard procedures for blood withdrawal in conscious male rats induce stress and profoundly affect glucose tolerance and secretion of glucoregulatory hormones

OBJECTIVE: A fundamental difference between physiological and pharmacological studies in rats and humans is that withdrawal of blood from conscious rats necessitates restraint which inevitably inflicts a higher level of stress. We investigated the impact of handling on acute glucose regulation and s...

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Detalles Bibliográficos
Autores principales: Pedersen, Kent, Andersen, Helle, Fledelius, Christian, Holst, Jens Juul, Hjuler, Sara Toftegaard, Kuhre, Rune Ehrenreich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950954/
https://www.ncbi.nlm.nih.gov/pubmed/36739969
http://dx.doi.org/10.1016/j.molmet.2023.101689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950954/
https://www.ncbi.nlm.nih.gov/pubmed/36739969
http://dx.doi.org/10.1016/j.molmet.2023.101689

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