Polypharmacy With High Drug Burden Index (DBI) Alters the Gut Microbiome Overriding Aging Effects and Is Reversible With Deprescribing

Aging, medication use, and global function are associated with changes in the microbiome. However, their interrelationships and changes over time require further characterization. In a longitudinal aging mouse study, we investigated the effects of aging, chronic polypharmacy with a high Drug Burden...

Descripción completa

Detalles Bibliográficos
Autores principales: Gemikonakli, Gizem, Mach, John, Zhang, Fan, Bullock, Martyn, Tran, Trang, El-Omar, Emad, Hilmer, Sarah N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
THE JOURNAL OF GERONTOLOGY: Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951051/
https://www.ncbi.nlm.nih.gov/pubmed/36124741
http://dx.doi.org/10.1093/gerona/glac195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951051/
https://www.ncbi.nlm.nih.gov/pubmed/36124741
http://dx.doi.org/10.1093/gerona/glac195

Ejemplares similares