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Glucosyl Platinum(II) Complexes Inhibit Aggregation of the C-Terminal Region of the Aβ Peptide

[Image: see text] Neurodegenerative diseases are often caused by uncontrolled amyloid aggregation. Hence, many drug discovery processes are oriented to evaluate new compounds that are able to modulate self-recognition mechanisms. Herein, two related glycoconjugate pentacoordinate Pt(II) complexes we...

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Detalles Bibliográficos
Autores principales: La Manna, Sara, Leone, Marilisa, Iacobucci, Ilaria, Annuziata, Alfonso, Di Natale, Concetta, Lagreca, Elena, Malfitano, Anna Maria, Ruffo, Francesco, Merlino, Antonello, Monti, Maria, Marasco, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951207/
https://www.ncbi.nlm.nih.gov/pubmed/35171608
http://dx.doi.org/10.1021/acs.inorgchem.1c03540