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The emerging role of MCPH1/BRIT1 in carcinogenesis

The MCPH1 gene, also known as BRCT-repeat inhibitor of hTERT expression (BRIT1), has three BRCA1 carboxyl-terminal domains which is an important regulator of DNA repair, cell cycle checkpoints and chromosome condensation. MCPH1/BRIT1 is also known as a tumour suppressor in different types of human c...

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Detalles Bibliográficos
Autores principales: Alsolami, Mona, Aboalola, Doaa, Malibari, Dolal, Alghamdi, Tariq, Alshekhi, Walaa, Jad, Hind, Rumbold-Hall, Rea, Altowairqi, Ahlam S., Bell, Sandra M., Alsiary, Rawiah Abdullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951231/
https://www.ncbi.nlm.nih.gov/pubmed/36845691
http://dx.doi.org/10.3389/fonc.2023.1047588