Cargando…

Comprehensive Structure–Activity Relationship Studies of Cepafungin Enabled by Biocatalytic C–H Oxidations

[Image: see text] The cepafungins are a class of highly potent and selective eukaryotic proteasome inhibitor natural products with potential to treat refractory multiple myeloma and other cancers. The structure–activity relationship of the cepafungins is not fully understood. This Article chronicles...

Descripción completa

Detalles Bibliográficos
Autores principales: Amatuni, Alexander, Shuster, Anton, Abegg, Daniel, Adibekian, Alexander, Renata, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951290/
https://www.ncbi.nlm.nih.gov/pubmed/36844499
http://dx.doi.org/10.1021/acscentsci.2c01219