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Comprehensive Structure–Activity Relationship Studies of Cepafungin Enabled by Biocatalytic C–H Oxidations
[Image: see text] The cepafungins are a class of highly potent and selective eukaryotic proteasome inhibitor natural products with potential to treat refractory multiple myeloma and other cancers. The structure–activity relationship of the cepafungins is not fully understood. This Article chronicles...
Autores principales: | Amatuni, Alexander, Shuster, Anton, Abegg, Daniel, Adibekian, Alexander, Renata, Hans |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951290/ https://www.ncbi.nlm.nih.gov/pubmed/36844499 http://dx.doi.org/10.1021/acscentsci.2c01219 |
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