Dose-Dependent Nuclear Delivery and Transcriptional Repression with a Cell-Penetrant MeCP2

[Image: see text] The vast majority of biologic-based therapeutics operate within serum, on the cell surface, or within endocytic vesicles, in large part because proteins and nucleic acids fail to efficiently cross cell or endosomal membranes. The impact of biologic-based therapeutics would expand e...

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Detalles Bibliográficos
Autores principales: Zhang, Xizi, Cattoglio, Claudia, Zoltek, Madeline, Vetralla, Carlo, Mozumdar, Deepto, Schepartz, Alanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951310/
https://www.ncbi.nlm.nih.gov/pubmed/36844491
http://dx.doi.org/10.1021/acscentsci.2c01226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951310/
https://www.ncbi.nlm.nih.gov/pubmed/36844491
http://dx.doi.org/10.1021/acscentsci.2c01226

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