CD73, a Promising Therapeutic Target of Diclofenac, Promotes Metastasis of Pancreatic Cancer through a Nucleotidase Independent Mechanism

CD73, a cell surface‐bound nucleotidase, facilitates extracellular adenosine formation by hydrolyzing 5′‐AMP to adenosine. Several studies have shown that CD73 plays an essential role in immune escape, cell proliferation and tumor angiogenesis, making it an attractive target for cancer therapies. Ho...

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Detalles Bibliográficos
Autores principales: Liu, Weishuai, Yu, Xiaozhou, Yuan, Yudong, Feng, Yixing, Wu, Chao, Huang, Chongbiao, Xie, Peng, Li, Shengnan, Li, Xiaofeng, Wang, Ziyang, Qi, Lisha, Chen, Yanan, Shi, Lei, Li, Mulin Jun, Huang, Zhiyong, Tang, Bo, Chang, Antao, Hao, Jihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951332/
https://www.ncbi.nlm.nih.gov/pubmed/36563135
http://dx.doi.org/10.1002/advs.202206335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951332/
https://www.ncbi.nlm.nih.gov/pubmed/36563135
http://dx.doi.org/10.1002/advs.202206335

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