ITDetect: a method to detect internal tandem duplication of FMS-like tyrosine kinase (FLT3) from next-generation sequencing data with high sensitivity and clinical application

Internal tandem duplication (ITD) of the FMS-like tyrosine kinase (FLT3) gene is associated with poor clinical outcomes in patients with acute myeloid leukemia. Although recent methods for detecting FLT3-ITD from next-generation sequencing (NGS) data have replaced traditional ITD detection approache...

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Detalles Bibliográficos
Autores principales: Lee, Sungyoung, Sun, Choong-Hyun, Jang, Heejun, Kim, Daeyoon, Yoon, Sung-Soo, Koh, Youngil, Na, Seung Chan, Cho, Sung Im, Kim, Man Jin, Seong, Moon-Woo, Byun, Ja Min, Yun, Hongseok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951415/
https://www.ncbi.nlm.nih.gov/pubmed/36823555
http://dx.doi.org/10.1186/s12859-023-05173-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951415/
https://www.ncbi.nlm.nih.gov/pubmed/36823555
http://dx.doi.org/10.1186/s12859-023-05173-8

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