Using protein-per-mRNA differences among human tissues in codon optimization

BACKGROUND: Codon usage and nucleotide composition of coding sequences have profound effects on protein expression. However, while it is recognized that different tissues have distinct tRNA profiles and codon usages in their transcriptomes, the effect of tissue-specific codon optimality on protein s...

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Detalles Bibliográficos
Autores principales: Hernandez-Alias, Xavier, Benisty, Hannah, Radusky, Leandro G., Serrano, Luis, Schaefer, Martin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951436/
https://www.ncbi.nlm.nih.gov/pubmed/36829202
http://dx.doi.org/10.1186/s13059-023-02868-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951436/
https://www.ncbi.nlm.nih.gov/pubmed/36829202
http://dx.doi.org/10.1186/s13059-023-02868-2

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