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Using protein-per-mRNA differences among human tissues in codon optimization
BACKGROUND: Codon usage and nucleotide composition of coding sequences have profound effects on protein expression. However, while it is recognized that different tissues have distinct tRNA profiles and codon usages in their transcriptomes, the effect of tissue-specific codon optimality on protein s...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951436/ https://www.ncbi.nlm.nih.gov/pubmed/36829202 http://dx.doi.org/10.1186/s13059-023-02868-2 |