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Whole transcriptome analysis to explore the impaired immunological features in critically ill elderly patients with sepsis

BACKGROUND: Sepsis is a frequent complication in critically ill patients, is highly heterogeneous and is associated with high morbidity and mortality rates, especially in the elderly population. Utilizing RNA sequencing (RNA-Seq) to analyze biological pathways is widely used in clinical and molecula...

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Detalles Bibliográficos
Autores principales: Chen, I-Chieh, Chen, Hsin-Hua, Jiang, Yu-Han, Hsiao, Tzu-Hung, Ko, Tai-Ming, Chao, Wen-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951485/
https://www.ncbi.nlm.nih.gov/pubmed/36823620
http://dx.doi.org/10.1186/s12967-023-04002-z