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Does multi-way, long-range chromatin contact data advance 3D genome reconstruction?
BACKGROUND: Methods for inferring the three-dimensional (3D) configuration of chromatin from conformation capture assays that provide strictly pairwise interactions, notably Hi-C, utilize the attendant contact matrix as input. More recent assays, in particular split-pool recognition of interactions...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951495/ https://www.ncbi.nlm.nih.gov/pubmed/36829114 http://dx.doi.org/10.1186/s12859-023-05170-x |