Human umbilical cord-derived mesenchymal stem cell transplantation supplemented with curcumin improves the outcomes of ischemic stroke via AKT/GSK-3β/β-TrCP/Nrf2 axis

BACKGROUND: Human umbilical cord-derived mesenchymal stem cell (hUC-MSC) engraftment is a promising therapy for acute ischemic stroke (AIS). However, the harsh ischemic microenvironment limits the therapeutic efficacy of hUC-MSC therapy. Curcumin is an anti-inflammatory agent that could improve infl...

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Detalles Bibliográficos
Autores principales: Li, Yuan, Huang, Jialu, Wang, Jie, Xia, Simin, Ran, Hong, Gao, Lenyu, Feng, Chengjian, Gui, Li, Zhou, Zhenhua, Yuan, Jichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951499/
https://www.ncbi.nlm.nih.gov/pubmed/36829224
http://dx.doi.org/10.1186/s12974-023-02738-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951499/
https://www.ncbi.nlm.nih.gov/pubmed/36829224
http://dx.doi.org/10.1186/s12974-023-02738-5

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