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Human umbilical cord-derived mesenchymal stem cell transplantation supplemented with curcumin improves the outcomes of ischemic stroke via AKT/GSK-3β/β-TrCP/Nrf2 axis

BACKGROUND: Human umbilical cord-derived mesenchymal stem cell (hUC-MSC) engraftment is a promising therapy for acute ischemic stroke (AIS). However, the harsh ischemic microenvironment limits the therapeutic efficacy of hUC-MSC therapy. Curcumin is an anti-inflammatory agent that could improve infl...

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Detalles Bibliográficos
Autores principales:	Li, Yuan, Huang, Jialu, Wang, Jie, Xia, Simin, Ran, Hong, Gao, Lenyu, Feng, Chengjian, Gui, Li, Zhou, Zhenhua, Yuan, Jichao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951499/ https://www.ncbi.nlm.nih.gov/pubmed/36829224 http://dx.doi.org/10.1186/s12974-023-02738-5

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