The total polyphenolic glycoside extract of Lamiophlomis rotata ameliorates hepatic fibrosis through apoptosis by TGF-β/Smad signaling pathway

BACKGROUND: Hepatic fibrosis is characterized by the excessive deposition of extracellular matrix (ECM) which is mainly secreted by activated hepatic stellate cells (HSCs). Lamiophlomis rotata (L. rotata) was recorded to treat jaundice in the traditional Tibetan medical system with the potential of...

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Detalles Bibliográficos
Autores principales: Wan, Guoguo, Chen, Zhiwei, Lei, Lei, Geng, Xiaoyu, Zhang, Yi, Yang, Congwen, Cao, Wenfu, Pan, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951520/
https://www.ncbi.nlm.nih.gov/pubmed/36829153
http://dx.doi.org/10.1186/s13020-023-00723-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951520/
https://www.ncbi.nlm.nih.gov/pubmed/36829153
http://dx.doi.org/10.1186/s13020-023-00723-x

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