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Whole‐Cell P450 Biocatalysis Using Engineered Escherichia coli with Fine‐Tuned Heme Biosynthesis
By exploiting versatile P450 enzymes, whole‐cell biocatalysis can be performed to synthesize valuable compounds in Escherichia coli. However, the insufficient supply of heme limits the whole‐cell P450 biocatalytic activity. Here a strategy for improving intracellular heme biosynthesis to enhance the...
Autores principales: | Hu, Baodong, Yu, Haibo, Zhou, Jingwen, Li, Jianghua, Chen, Jian, Du, Guocheng, Lee, Sang Yup, Zhao, Xinrui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951570/ https://www.ncbi.nlm.nih.gov/pubmed/36526588 http://dx.doi.org/10.1002/advs.202205580 |
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