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Sinomenine alleviates diabetic peripheral neuropathic pain through inhibition of the inositol‐requiring enzyme 1 alpha–X‐box binding protein 1 pathway by downregulating prostaglandin‐endoperoxide synthase 2

INTRODUCTION: We tried to show the effect of sinomenine (SIN) in diabetic peripheral neuropathic pain (DPNP) and the related underlying mechanism. METHODS: Network pharmacological analysis and bioinformatics analysis were carried out for identification of the active ingredients of Sinomenium acutum...

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Detalles Bibliográficos
Autores principales: Chen, Ji, Guo, Peng, Liu, Xinxin, Liao, Huizhi, Chen, Kemin, Wang, Yuxia, Qin, Jie, Yang, Fengrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951574/
https://www.ncbi.nlm.nih.gov/pubmed/36692011
http://dx.doi.org/10.1111/jdi.13938