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Specialized endothelial tip cells guide neuroretina vascularization and blood-retina-barrier formation

Endothelial tip cells guiding tissue vascularization are primary targets for angiogenic therapies. Whether tip cells require differential signals to develop their complex branching patterns remained unknown. Here, we show that diving tip cells invading the mouse neuroretina (D-tip cells) are distinc...

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Detalles Bibliográficos
Autores principales: Zarkada, Georgia, Howard, Joel P., Xiao, Xue, Park, Hyojin, Bizou, Mathilde, Leclerc, Severine, Künzel, Steffen E., Boisseau, Blanche, Li, Jinyu, Cagnone, Gael, Joyal, Jean Sebastien, Andelfinger, Gregor, Eichmann, Anne, Dubrac, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951594/
https://www.ncbi.nlm.nih.gov/pubmed/34273276
http://dx.doi.org/10.1016/j.devcel.2021.06.021