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Selective depletion of regulatory T cells enhances the immunogenicity of a recombinant-based vaccine against Sporothrix spp

INTRODUCTION: Regulatory T cells (Tregs) have been shown to limit the protective immune response against pathogenic species of the fungus Sporothrix spp, the causal agent of sporotrichosis. However, the specific function of Tregs during vaccination against these fungi is known. METHODS: We evaluated...

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Detalles Bibliográficos
Autores principales: Batista-Duharte, Alexander, Téllez-Martínez, Damiana, Portuondo, Deivys Leandro, Carlos, Iracilda Zeppone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951613/
https://www.ncbi.nlm.nih.gov/pubmed/36846549
http://dx.doi.org/10.3389/fcimb.2022.1084526