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Selective depletion of regulatory T cells enhances the immunogenicity of a recombinant-based vaccine against Sporothrix spp
INTRODUCTION: Regulatory T cells (Tregs) have been shown to limit the protective immune response against pathogenic species of the fungus Sporothrix spp, the causal agent of sporotrichosis. However, the specific function of Tregs during vaccination against these fungi is known. METHODS: We evaluated...
Autores principales: | Batista-Duharte, Alexander, Téllez-Martínez, Damiana, Portuondo, Deivys Leandro, Carlos, Iracilda Zeppone |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951613/ https://www.ncbi.nlm.nih.gov/pubmed/36846549 http://dx.doi.org/10.3389/fcimb.2022.1084526 |
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