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Nonalcoholic Fatty Liver Disease Is a Risk Factor for Thiopurine Hepatotoxicity in Crohn’s Disease

BACKGROUND: Patients with Crohn’s disease (CD) are predisposed to nonalcoholic fatty liver disease (NAFLD). CD management often includes thiopurines which can promote hepatotoxicity. We aimed to identify the role of NAFLD on the risk of developing liver injury from thiopurines in CD. METHODS: In thi...

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Detalles Bibliográficos
Autores principales: George, Alvin T, Glover, Matthew, Alayo, Quazim, Zulfiqar, Maria, Ludwig, Daniel R, Ciorba, Matthew A, McHenry, Scott, Deepak, Parakkal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951740/
https://www.ncbi.nlm.nih.gov/pubmed/36846096
http://dx.doi.org/10.1093/crocol/otad005