Cargando…

Manipulation of diacylglycerol and ERK-mediated signaling differentially controls CD8(+) T cell responses during chronic viral infection

INTRODUCTION: Activation of T cell receptor (TCR) signaling is critical for clonal expansion of CD8+ T cells. However, the effects of augmenting TCR signaling during chronic antigen exposure is less understood. Here, we investigated the role of diacylglycerol (DAG)-mediated signaling downstream of t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Harabuchi, Shohei, Khan, Omar, Bassiri, Hamid, Yoshida, Taku, Okada, Yohei, Takizawa, Masaomi, Ikeda, Osamu, Katada, Akihiro, Kambayashi, Taku
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951774/ https://www.ncbi.nlm.nih.gov/pubmed/36846018 http://dx.doi.org/10.3389/fimmu.2022.1032113

Ejemplares similares

The Immunomodulatory Functions of Diacylglycerol Kinase ζ
por: Singh, Brenal K., et al.
Publicado: (2016)

Regulation of Airway Smooth Muscle Cell Proliferation by Diacylglycerol Kinase: Relevance to Airway Remodeling in Asthma
por: Hernandez-Lara, Miguel Angel, et al.
Publicado: (2022)

Genetic manipulation of the interconversion between diacylglycerols and triacylglycerols in Rhodosporidium toruloides
por: Zhang, Yue, et al.
Publicado: (2022)

Genotoxicity evaluation of alpha-linolenic acid-diacylglycerol oil
por: Honda, Hiroshi, et al.
Publicado: (2016)

Diacylglycerol lipase α manipulation reveals developmental roles for intercellular endocannabinoid signaling
por: Keimpema, Erik, et al.
Publicado: (2013)

Diacylglycerol oil for the metabolic syndrome
por: Yanai, Hidekatsu, et al.
Publicado: (2007)

TCR signaling by conventional CD4(+) T cells is required for optimal maintenance of peripheral regulatory T cell numbers
por: Leichner, Theresa M., et al.
Publicado: (2016)

Acute Manipulation of Diacylglycerol Reveals Roles in Nuclear Envelope Assembly & Endoplasmic Reticulum Morphology
por: Domart, Marie-Charlotte, et al.
Publicado: (2012)

Various Molecular Species of Diacylglycerol Hydroperoxide Activate Human Neutrophils via PKC Activation
por: Kambayashi, Yasuhiro, et al.
Publicado: (2007)

Diacylglycerol kinase ζ controls diacylglycerol metabolism at the immunological synapse
por: Gharbi, Severine I., et al.
Publicado: (2011)

Endoscopic submucosal dissection of cervical esophageal cancer with hypopharyngeal invasion using a curved laryngoscope
por: Furue, Yasuaki, et al.
Publicado: (2021)

Engineering the Thermostability of the Mono- and Diacylglycerol Lipase SMG1 for the Synthesis of Diacylglycerols
por: Li, Lilang, et al.
Publicado: (2022)

Crosstalk between regulatory T cells (Tregs) and myeloid derived suppressor cells (MDSCs) during melanoma growth
por: Fujimura, Taku, et al.
Publicado: (2012)

Immunomodulatory Effect of Bisphosphonate Risedronate Sodium on CD163(+) Arginase 1(+) M2 Macrophages: The Development of a Possible Supportive Therapy for Angiosarcoma
por: Fujimura, Taku, et al.
Publicado: (2013)

Sarcoidosis-Lymphoma Syndrome Associated with Folliculotropic Peripheral T Cell Lymphoma Not Otherwise Specified
por: Yoshida, Saaya, et al.
Publicado: (2017)

Successful Treatment of Multiple Metastatic Melanoma with Nivolumab, Ipilimumab plus Denosumab Combined Therapy
por: Yoshida, Saaya, et al.
Publicado: (2019)

Diacylglycerol Kinases: Shaping Diacylglycerol and Phosphatidic Acid Gradients to Control Cell Polarity
por: Baldanzi, Gianluca, et al.
Publicado: (2016)

Novel compound heterozygous CDH23 variants in a patient with Usher syndrome type I
por: Okano, Satomi, et al.
Publicado: (2019)

ANCA-Negative Granulomatosis with Polyangiitis Presenting with Hypertrophic Cranial Pachymeningitis, Abducens Nerve Palsy, and Stenosis of the Internal Carotid Artery
por: Harabuchi, Shohei, et al.
Publicado: (2017)

Editorial: Diacylglycerol Kinase Signalling
por: Merida, Isabel, et al.
Publicado: (2017)

Diacylglycerol Kinases in Signal Transduction
por: Centonze, Sara, et al.
Publicado: (2022)

Therapy-Resistant, Spontaneously Remitting Generalized Neutrophilic Eccrine Hidradenitis in a Healthy Patient Decreases the Expression of Dermcidin in Affected Eccrine Glands
por: Kambayashi, Yumi, et al.
Publicado: (2011)

Basal Cell Carcinoma with Spontaneous Regression: A Case Report and Immunohistochemical Study
por: Fujimura, Taku, et al.
Publicado: (2012)

Profiles of Cytotoxic T Lymphocytes in Cutaneous Lymphoid Hyperplasia of the Face
por: Furudate, Sadanori, et al.
Publicado: (2013)

Potential Use of Bisphosphonates in Invasive Extramammary Paget's Disease: An Immunohistochemical Investigation
por: Fujimura, Taku, et al.
Publicado: (2013)

Granulysin-Bearing Cells in the Skin Lesions of Acute Graft-versus-Host Disease: Possible Mechanisms for Hypohidrosis in Graft-versus-Host Disease
por: Furudate, Sadanori, et al.
Publicado: (2013)

Biomarkers for Predicting Efficacies of Anti-PD1 Antibodies
por: Kambayashi, Yumi, et al.
Publicado: (2019)

Significance of BRAF Kinase Inhibitors for Melanoma Treatment: From Bench to Bedside
por: Fujimura, Taku, et al.
Publicado: (2019)

Topical and Systemic Formulation Options for Cutaneous T Cell Lymphomas
por: Fujimura, Taku, et al.
Publicado: (2021)

Plasminogen Activating Inhibitor-1 Might Predict the Efficacy of Anti-PD1 Antibody in Advanced Melanoma Patients
por: Ohuchi, Kentaro, et al.
Publicado: (2021)

Association of diacylglycerol kinase ζ with protein kinase C α: spatial regulation of diacylglycerol signaling
por: Luo, Bai, et al.
Publicado: (2003)

Systemic Lupus Erythematosus Accompanied by Psoriasis Induces IL-27-Producing Cells in Both Affected Areas of the Skin
por: Tojo, Gen-ichi, et al.
Publicado: (2012)

Inhibition of Calcineurin Abrogates While Inhibition of mTOR Promotes Regulatory T Cell Expansion and Graft-Versus-Host Disease Protection by IL-2 in Allogeneic Bone Marrow Transplantation
por: Satake, Atsushi, et al.
Publicado: (2014)

The association between low pH value and unfavorable neurological outcome among the out-of-hospital cardiac arrest patient treated by extra-corporeal CPR: sensitivity analysis
por: Okada, Yohei, et al.
Publicado: (2020)

A molecular mechanism for diacylglycerol-mediated promotion of negative caloric balance
por: Yanai, Hidekatsu, et al.
Publicado: (2009)

Assembly of the tight junction: the role of diacylglycerol
Publicado: (1993)

Regulation of Macropinocytosis by Diacylglycerol Kinase ζ
por: Ard, Ryan, et al.
Publicado: (2015)

Diacylglycerol Kinases in the Coordination of Synaptic Plasticity
por: Lee, Dongwon, et al.
Publicado: (2016)

slr2103, a homolog of type-2 diacylglycerol acyltransferase genes, for plastoquinone-related neutral lipid synthesis and NaCl-stress acclimatization in a cyanobacterium, Synechocystis sp. PCC 6803
por: Kondo, Mimari, et al.
Publicado: (2023)

AGPAT2 interaction with CDP-diacylglycerol synthases promotes the flux of fatty acids through the CDP-diacylglycerol pathway
por: Mak, Hoi Yin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_vkada06n2cpntthnaqrae8tqps