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In silico screening of Andrographis paniculata secondary metabolites as anti-diabetes mellitus through PDE9 inhibition
BACKGROUND AND PURPOSE: Andrographis paniculata (AP) has long been used as an anti-diabetic agent, but the mechanism of action and active substance responsible for the anti-diabetic effect, particularly by inhibiting phosphodiesterase-9 (PDE9), which is one of the targets of anti-diabetic medication...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951786/ https://www.ncbi.nlm.nih.gov/pubmed/36846729 http://dx.doi.org/10.4103/1735-5362.363616 |