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Experimental venous thrombus resolution is driven by IL-6 mediated monocyte actions

Deep venous thrombosis and residual thrombus burden correlates with circulating IL-6 levels in humans. To investigate the cellular source and role of IL-6 in thrombus resolution, Wild type C57BL/6J (WT), and IL-6(−/−) mice underwent induction of VT via inferior vena cava (IVC) stenosis or stasis. Ve...

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Detalles Bibliográficos
Autores principales: Obi, Andrea T., Sharma, Sriganesh B., Elfline, Megan A., Luke, Catherine E., Dowling, Abigail R., Cai, Qing, Kimball, Andrew S., Hollinstat, Mike, Stanger, Livia, Moore, Bethany B., Jaffer, Farouc A., Henke, Peter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951841/
https://www.ncbi.nlm.nih.gov/pubmed/36828892
http://dx.doi.org/10.1038/s41598-023-30149-2