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Somatically hypermutated antibodies isolated from SARS-CoV-2 Delta infected patients cross-neutralize heterologous variants

SARS-CoV-2 Omicron variants feature highly mutated spike proteins with extraordinary abilities in evading antibodies isolated earlier in the pandemic. Investigation of memory B cells from patients primarily with breakthrough infections with the Delta variant enables isolation of a number of neutrali...

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Detalles Bibliográficos
Autores principales: Yu, Haisheng, Liu, Banghui, Zhang, Yudi, Gao, Xijie, Wang, Qian, Xiang, Haitao, Peng, Xiaofang, Xie, Caixia, Wang, Yaping, Hu, Peiyu, Shi, Jingrong, Shi, Quan, Zheng, Pingqian, Feng, Chengqian, Tang, Guofang, Liu, Xiaopan, Guo, Liliangzi, Lin, Xiumei, Li, Jiaojiao, Liu, Chuanyu, Huang, Yaling, Yang, Naibo, Chen, Qiuluan, Li, Zimu, Su, Mengzhen, Yan, Qihong, Pei, Rongjuan, Chen, Xinwen, Liu, Longqi, Hu, Fengyu, Liang, Dan, Ke, Bixia, Ke, Changwen, Li, Feng, He, Jun, Wang, Meiniang, Chen, Ling, Xiong, Xiaoli, Tang, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951844/
https://www.ncbi.nlm.nih.gov/pubmed/36828833
http://dx.doi.org/10.1038/s41467-023-36761-0