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Itaconate Suppresses the Activation of Mitochondrial NLRP3 Inflammasome and Oxidative Stress in Allergic Airway Inflammation

Itaconate has emerged as a novel anti-inflammatory and antioxidative endogenous metabolite, yet its role in allergic airway inflammation (AAI) and the underlying mechanism remains elusive. Here, the itaconate level in the lung was assessed by High Performance Liquid Chromatography (HPLC), and the ef...

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Detalles Bibliográficos
Autores principales: Xie, Qiu-Meng, Chen, Ning, Song, Si-Ming, Zhao, Cui-Cui, Ruan, Ya, Sha, Jia-Feng, Liu, Qian, Jiang, Xu-Qin, Fei, Guang-He, Wu, Hui-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951851/
https://www.ncbi.nlm.nih.gov/pubmed/36830047
http://dx.doi.org/10.3390/antiox12020489