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Itaconate Suppresses the Activation of Mitochondrial NLRP3 Inflammasome and Oxidative Stress in Allergic Airway Inflammation
Itaconate has emerged as a novel anti-inflammatory and antioxidative endogenous metabolite, yet its role in allergic airway inflammation (AAI) and the underlying mechanism remains elusive. Here, the itaconate level in the lung was assessed by High Performance Liquid Chromatography (HPLC), and the ef...
Autores principales: | Xie, Qiu-Meng, Chen, Ning, Song, Si-Ming, Zhao, Cui-Cui, Ruan, Ya, Sha, Jia-Feng, Liu, Qian, Jiang, Xu-Qin, Fei, Guang-He, Wu, Hui-Mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951851/ https://www.ncbi.nlm.nih.gov/pubmed/36830047 http://dx.doi.org/10.3390/antiox12020489 |
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