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Synthesis of New Shogaol Analogues as NRF2 Activators and Evaluation of Their Anti-Inflammatory Activity, Modes of Action and Metabolic Stability

6-shogaol is a natural and the most potent bioactive vanilloid in dried Zingiber officinale rhizomes. Many scientific studies have reported the diverse biological activities of 6-shogaol. However, the major drawback of 6-shogaol is its instability at room temperature. We synthesised new shogaol thio...

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Detalles Bibliográficos
Autores principales: Mak, Kit-Kay, Shiming, Zhang, Sakirolla, Raghavendra, Balijepalli, Madhu Katyayani, Dinkova-Kostova, Albena T., Epemolu, Ola, Mohd, Zulkefeli, Pichika, Mallikarjuna Rao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951879/
https://www.ncbi.nlm.nih.gov/pubmed/36830033
http://dx.doi.org/10.3390/antiox12020475