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CHIP Haploinsufficiency Exacerbates Hepatic Steatosis via Enhanced TXNIP Expression and Endoplasmic Reticulum Stress Responses

TXNIP is a critical regulator of glucose homeostasis, fatty acid synthesis, and cholesterol accumulation in the liver, and it has been reported that metabolic diseases, such as obesity, atherosclerosis, hyperlipidemia, type 2 diabetes, and nonalcoholic fatty liver disease (NAFLD), are associated wit...

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Detalles Bibliográficos
Autores principales: Han, Jung-Hwa, Nam, Dae-Hwan, Kim, Seon-Hui, Hwang, Ae-Rang, Park, So-Young, Lim, Jae Hyang, Woo, Chang-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951908/
https://www.ncbi.nlm.nih.gov/pubmed/36830016
http://dx.doi.org/10.3390/antiox12020458